Programme
Abstract Book
All lectures and poster sessions will take place in the Manez (Old Riding School) Conference Hall.
All posters will be viewed during the whole time of the conference. Please, place your poster in the Manez Lecture Room immediately after arrival and dismount it not earlier than after the CLOSING LECTURE.
Wednesday, 15 May 2013
15:00 - 22:00 REGISTRATION
18:00 - 19:30 WELCOME RECEPTION - GARDEN PARTY
OPENING LECTURE
chairperson: Marek Cieplak
19:30 - 20:15 Jane Clarke, University of Cambridge, Department of Chemistry, UK
Lessons that can be learned from studying the folding of protein families
20:15 - 20:25 Anna Niedzwiecka, Institute of Physics PAS; University of Warsaw, Poland
National Multidisciplinary Laboratory of Functional Nanomaterials POIG 2.2 - NanoFun
20:30 - 22:00 DINNER AT BONFIRE
Thursday, 16 May 2013
SESSION I FOLDING
chairperson: Marek Cieplak
9:00 - 9:30 Jasna Brujic, New York University, USA
Views of protein folding from a statistical physics approach to single molecule experiments
9:30 - 10:00 Thomas Kiefhaber, Technical Univeristy Munich, Germany
The unlocked state: a clue to understand how proteins fold and unfold
10:00 - 10:30 Andrzej Kolinski, University of Warsaw, Poland
CABS - coarse grained modeling of protein structure assembly, dynamics and interactions
10:30 - 11:00 COFFEE BREAK
chairperson: Jasna Brujic
11:00 - 11:30 George Stan, University of Cincinnati, USA
Computer simulations of protein unfoldimg and translocation by AAA+ chaperones
11:30 - 12:00 Joan-Emma Shea, University of California Santa Barbara, USA
Effect of surfaces in modulating protein folding
12:00 - 12:30 Patricia Faisca, University of Lisboa, Portugal
Intermediate states for protein folding and aggregation
12:30 - 12:45 Roberto Covino, University of Trento, INFN, Italy
Protein folding pathways with realistic atomistic force fields
12:45 - 13:00 Annett Bachmann, Technical Univeristy Munich, Germany
The Mechanism of a Coupled Protein Folding and Binding Reaction: Folding Before Binding
or Binding Before Folding?
13:00 - 14:30 LUNCH
SESSION II COMPLEXES AND RECOGNITION
chairperson: Thomas Kiefhaber
14:30 - 15:00 Rebecca C. Wade, Heidelberg Institute for Theoretical Studies; Heidelberg University, Germany
Protein dynamics and molecular recognition: Insights from simulations
15:00 - 15:30 Joanna Trylska, CeNT, University of Warsaw, Poland
Ribosomal RNA as a target for sequence-specific inhibition
15:30 - 16:00 Adam Liwo, University of Gdansk, POLAND
Mean field dipole-dipole interactions as essential factors in the formation of biomolecular
architecture
16:00 - 16:30 COFFEE BREAK
16:30 - 17:00 Peter Hinterdorfer, Johannes Kepler University Linz, Austria
Molecular recognition force microscopy/spectroscopy
17:00 - 17:30 Ruxandra Dima, University of Cincinnati, USA
Multiscale simulations of the mechanics of filamentous proteins
17:30 - 18:00 Pawel Pomorski, Nencki Institute of Experimental Biology PAS, Warsaw, Poland
How cell adhesion can influence nucleotide-dependent calcium signal: the idea of
signalosome and it's practical implementation
18:00 - 18:15 Michal Toborek, University of Miami School of Medicine, USA
Autophagy is involved in nanoalumina-induced cerebrovascular toxicity
18:15 - 18:30 Juergen Schluetter, LOT-Quantum Design, Germany
Studying of protein aggregation onto surfaces using QCM-D
18:30 - 19:45 DINNER
20:00 - 22:00 POSTER SESSION I - odd numbers presenting authors
Friday, 17 May 2013
SESSION III MOLECULAR COMPLEXES IN GENE EXPRESSION
chaiperson: Anna Niedzwiecka
9:00 - 9:30 Marc Fabian, McGill University, Montreal, Canada
Structural insight into gene silencing programs that employ the CCR4-NOT deadenylase
complex
9:30 - 10:00 Marek Tchorzewski, Maria Curie-Sklodowska University, Lublin, Poland
The ribosome action as transitions between different functional/structural states driven by
energy obtained from GTP hydrolysis
10:00 - 10:30 Piotr Zielenkiewicz, Institute of Biochemistry and Biophysics PAS, Warsaw, Poland
Whole cell model of translation
10:30 - 11:00 COFFEE BREAK
SESSION IV BIO-NANO
chairperson: Giovanni Dietler
11:00 - 11:30 Andrzej Sienkiewicz, EPFL, Lausanne, Switzerland
Multifunctional magnetic-photoluminescent-photocatalytic nanostructures for biomedical
applications
The European Physical Society Invited Lecture
11:30 - 12:00 Damien Thompson, Tyndall Institute, Cork, Ireland
Nanoscale computer-aided design of self-assembling materials for electronics and health
applications
12:00 - 12:30 Piotr Garstecki, Institute of Physical Chemistry PAS, Warsaw, Poland
Automated droplet microfluidics for studies of emergence of drug resistance in bacteria
12:30 - 13:00 Robert Leheny, Johns Hopkins Univeristy, Baltimore, USA
Viscoelastic behavior of proteinic surfaces
13:00 - 16:30 LUNCH & FREE TIME
16:30 - 17:00 COFFEE BREAK
chairperson: Joan Emma Shea
17:00 - 17:30 Robert Holyst, Institute of Physical Chemistry PAS, Warsaw, Poland
Biologistics: mobility of ligands, proteins and plasmids in cytoplasm of the eukaryotic and
prokaryotic cells
17:30 - 18:00 Jaroslaw Stolarski, Institute of Paleobiology PAS, Warsaw, Poland
How meaningful is prefix "bio" for minerals formed by organisms: the nanoscale perspective
18:00 - 18:30 Boguslaw Baginski, University of Warsaw, Poland
Zircon - small but great
18:30 - 19:45 DINNER
20:00 - 22:00 POSTER SESSION II - even numbers presenting authors
Saturday, 18 May 2013
SESSION V PROTEIN STRUCTURE
chairperson: Mariusz Jaskólski
9:00 - 9:30 Catherine Royer, Centre de Biochemie Structurale, Montpelier, France
Pressure effects on protein stability - the devil is in the details
9:30 - 10:00 Wladek Minor, University of Virginia, Charlottesville, USA
Experiment and modeling: competitive or complementary approaches to structural biology?
10:00 - 10:30 Andrzej Kloczkowski, Nationwide Children's Hospital, Columbus, OH, USA
New methods to improve protein structure prediction and refinement
10:30 - 10:45 Agnieszka J. Pietrzyk, Institute of Bioorganic Chemistry, PAS, Poznan, Poland
Structural studies on 30-kDa lipoproteins from mulberry silkworm
10:45 - 11:15 COFFEE BREAK
SESSION VI VIRUSES
chairperson: Catherine Royer
11:15 - 11:45 Gijs Wuite, Vrije Universiteit, Amsterdam, Holland
The nanomechanics of viruses
11:45 - 12:15 Neil Ferguson, University College Dublin, Ireland
Molecular mimicry in hepatitis B virus: How a viral intrinsically disordered protein helps
hijacks the host membrane-trafficking machinery
12:15 - 12:45 Wouter Roos, Vrije Universiteit, Amsterdam, Holland
Dual structural role of the viral RNA: capsid stabilization vs. genome uncoating
12:45 - 13: 15 Cristian Micheletti, SISSA, Trieste, Italy
DNA knotting inside viral capsids: a computational approach
13:15 - 15:15 LUNCH
SESSION VII DNA
chairperson: Cristian Micheletti
15:15 - 15:45 Giovanni Dietler, EPFL, Lausanne, Switzerland
Knots: from the sailing boat down to the cell's nucleus illustrated by means of simple
experiments
15:45 - 16:15 Andrew Travers, LMB, Cambridge, UK
Chromosomes as topological machines
16:15 - 16:45 Joerg Rottler, University of British Columbia, Vancouver, Canada
Predictions of a systematically coarse grained model for DNA
16:45 - 17:15 COFFEE BREAK
SESSION VIII FINALE
chairperson: Chris Johnson
17:15 - 17:45 Amos Maritan, University of Padua, Italy
Emergence of criticality in living systems
17:45 - 18:15 Annalisa Pastore, National Institute for Medical Research, MRC, London, UK
Kaleidoscopic protein self-assembly: The AXH domain of ataxin-1 undergoes a complex
multiple equilibrium of species in solution
18:15 - 18:45 Mariusz Jaskolski, Institute of Bioorganic Chemistry, PAS; Adam Mickiewicz University, Poznan,
Poland
Modulated macromolecular crystal structure with 28 protein molecules in the asymmetric
unit
CLOSING LECTURE
18:45 - 19:30 Gerhard Hummer, NIH Bethesda, USA
Order and disorder in biomolecular assemblies
20:00 CONFERENCE BANQUET
Sunday, 19 May 2013
7:30 - 10:00 BREAKFAST
8:30 DEPARTURE I
10:00 or 11:00 DEPARTURE II
